D12 — Data Reliability, Ethics, and Assessment Limits
Cultural and Contextual Limits
Description
Language, culture, neurodiversity, age, disability, or digital norms may affect interpretation.
Rationale
Cultural, linguistic, neurological, and developmental context shapes how AI is used and what that use means. Behaviors that appear concerning in one context may be normative or misinterpreted in another. Evaluators working across cultural or linguistic differences, or with individuals with neurodevelopmental conditions or age-related vulnerabilities, must account for these limits.
Evidence Base
Independent Clinical Evaluation of General-Purpose LLM Responses to Signals of Suicide Risk
Nick Judd, Alexandre Vaz, Kevin Paeth, Layla Inés Davis, Milena Esherick, Jason Brand, Inês Amaro, Tony Rousmaniere, 2024. Independent Clinical Evaluation of General-Purpose LLM Responses to Signals of Suicide Risk. Proceedings of the Second International Association for Safe and Ethical AI Conference (IASEAI’26), 279. DOI: null.
Peer-reviewed study (original research)AI-associated delusions: the missing dimension of mortality
Idris Altinisik, Utku Igcioglu, Murat Emul, 2024. AI-associated delusions: the missing dimension of mortality. Lancet Psychiatry, Vol 13, pages 456. https://doi.org/10.1016/S2215-0366(25)00396-7.
Commentary / EditorialBuilding safer artificial intelligence mental health chatbots: a framework for transparency, evaluation, and shared accountability
Hannah Lee, BS, Rebecca Handler, MSc, Tushar Mungle, PhD, Tina Hernandez-Boussard, PhD, 2026. Building safer artificial intelligence mental health chatbots: a framework for transparency, evaluation, and shared accountability. Journal of the American Medical Informatics Association, 33(8), 1538–1553. https://doi.org/10.1093/jamia/ocag078
Peer-reviewed study (original research)Artificial Intelligence, Extremism and Prevention of Radicalisation: Effective use of AI in P/CVE Post-Event Paper
Javier Ruipérez & Arije Antinori, 2024. Artificial Intelligence, Extremism and Prevention of Radicalisation: Effective use of AI in P/CVE Post-Event Paper. EU Knowledge Hub on Prevention of Radicalisation.
Government / agency reportAI chatbot-associated psychiatric symptoms: a narrative review of publicly available reports and media accounts
Arun, A., Trinh, C., & IsHak, W. W., 2026. AI chatbot-associated psychiatric symptoms: a narrative review of publicly available reports and media accounts. Discover Mental Health, Article in Press. https://doi.org/10.1007/s44192-026-00619-w
Narrative reviewHuman-in-the-Loop Suicide Risk Detection and Clinical Escalation in a Generative AI Mental Health Chatbot: Prospective Implementation Study
Suzette Glasner, Darcy Michero, Matthew Stewart, 2026. Human-in-the-Loop Suicide Risk Detection and Clinical Escalation in a Generative AI Mental Health Chatbot: Prospective Implementation Study. JMIR Preprints. DOI: https://doi.org/10.2196/preprints.106118.
Preprint